Sublingual methyl-B12 is a dietary supplement that provides vitamin B12 in the form of methylcobalamin. The sublingual form dissolves quickly and is easily absorbed in the bloodstream through sublingual tissues. Sublingual methyl-B12 supplements sometimes contain natural sweetening and dispersing agents such as mannitol and xylitol.
Methylcobalamin is one of the two active coenzymes forms of Vitamin B12 and plays an important role in many body functions. Methylcobalamin helps in the formation of red blood cells and thus controls pernicious and megaloblastic anemia. It also plays a part in the synthesis and function of nerve tissues. Methylcobalamin assists brain and nervous system functions, methylation reactions, and immune system regulation. Metabolism of fats, carbohydrates and proteins for energy release are also aided by methylcobalamin.
Methylcobalamin also serves as a coenzyme for the biosynthesis of methyl groups. Methyl groups act as essential cofactor for methionine synthase, which is an important enzyme necessary for the synthesis of methionine from homocysteine. This contributes in turn to the lowering of the homocysteine levels, an amino acid which plays an important role in increasing the risk of cardiovascular heart diseases. Methylcobalamin neutralizes harmful homocysteine, ands helps in heart diseases. Children with regressive autism possess unique metabolic bio chemistry. Autistic children with biochemical abnormalities are proven to show significant improvements in complex immune, neurological, and metabolic impairments, with the use of methyl B 12 supplements.
Recent data has shown that patients with neuropathies have benefited from the use of methylcobalamin. Methylcobalamin helps regenerate damage neurons, and insulate nerve fibers. Mental dysfunction in the older people can also be attended to with the help of oral supplements of sublingual methyl B12. Patients with uremia or uremic-diabetic polyneuropathies have shown significant improvement in sensory nerve conduction velocities. The use of methylcobalamin with folic acid helps hemodialysis patients by deceasing total plasma homocysteine levels.
Methylcobalamin can also be used as an Adjunct in Protocols for celiac disease, asthma and sulfite sensitivity, detoxification of brain tissues, prevention of peripheral nerve damage in cases including multiple sclerosis and diabetes. Nerve damage due to chemotherapy can also be addressed through the administration of methylcobalamin. Methylcobalamin has also been tested to benefit alleviating the mood and preventing depression, by the enhanced production of melatonin and seratonin. It can also be used adjunct in low sperm count treatments, and also to treat AIDS to some extent.
Evidence suggests that methylcobalamin has therapeutic applications and metabolic benefits that cannot be offered by other forms of vitamin B12. Other forms of B12 need to be converted to allow for use by the body. Patients with enzyme defects, tissue abnormalities, and nutritional adequacies cannot synthesize the other forms for use. But methylcobalamin is itself the most active and effective form, and thus needs no conversion in the body for its use.
Dietary supplements of methylcobalamin such as in sublingual methyl B12 are safe and are also well tolerated. Adverse reactions are usually not reported, and thus can be taken everyday.
A number of well known medicinal suppliers provide sublingual methyl B12 supplements, such as Health Product Distributors, vitabase, and Applied ProLine. Apart from vitamin B12, other ingredients commonly found in such tablets are vitamin B6, biotin, micro crystalline cellulose, folic acid, fructose, sorbitol, mannitol, dextrose, natural cherry flavor, magnesium stearate, silica etc. Prices of such products can range from $16 to $22.
One sublingual methyl B12 supplement is to be taken daily. It should be left for two to three minutes in the mouth until completely dissolved. Use of methyl B12 supplements should be used at different times of the day if other medications are being administered. This is because certain medications for diabetes, ulcers, or seizure disorders may get in the way of the body’s ability to absorb methylcobalamin.
Sublingual methyl B12 provides the most active form of B12 and is available as well. It is quickly absorbed in the bloodstream. It can help heighten energy, prevent heart diseases, improves mental attentiveness, and also provides a number of other benefits for the body. It is particularly helpful in patient with weak methylation capacity and increased neurological and homocysteine impairments.
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